Are Cattle a Surrogate Model for Pathogenic Mycobacterial Latent Infection?

In Vitro Model of Latent Mycobacterial Infection

In vitro model of latent mycobacterial infection (DIV II)

In vitro model of latent mycobacterial infection (DIV I)

A silkworm model of pathogenic bacterial infection.

Silkworms are invertebrate animals that are killed by bacteria pathogenic against humans, such as Staphylococcus aureus, Streptococcus pyogenes, Pseudomonas aeruginosa, and Vibrio cholerae. Injection into the hemolymph of antibiotics that are clinically used for human patients abolishes the killing effects. There are several advantages to using silkworms as an infection model, such as low cost,...

Mycobacterial infection.

Tuberculosis and leprosy are two well known mankind diseases that are caused by members of the genus Mycobacterium. When originally named in 1896, this genus contained the leprosy bacillus (Mycobacterium leprae) observed by Armour Hansen in 1874 and the tubercle bacillus (Mycobacterium tuberculosis) observed and cultured by Robert Koch in 1882. As time went by, other bacilli similar to those of...